Sitaform (Sitagliptin+Metformin)

Sitagliptin and metformin are often combined in a single medication for the management of type 2 diabetes mellitus. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of incretin hormones, which stimulate insulin release and reduce glucagon secretion, thereby lowering blood sugar levels. Metformin is a biguanide medication that works primarily by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, leading to reduced blood sugar levels. By combining sitagliptin and metformin, this medication offers a dual mechanism of action to help control blood sugar levels in individuals with type 2 diabetes. It is typically taken orally and is generally well-tolerated, but it may cause side effects such as gastrointestinal upset, including diarrhea and abdominal discomfort. Therefore, it's essential to use this combination medication under the guidance of a healthcare professional and to follow the recommended dosage and monitoring. Additionally, individuals taking sitagliptin and metformin should follow a healthy lifestyle, including a balanced diet and regular exercise, to optimize blood sugar control.