Colhetz (Colistimethate)
Colhetz (Colistimethate)
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Colistimethate is a potent antibiotic reserved for serious gram-negative bacterial infections when other treatments have failed. This injectable medication works by disrupting bacterial cell membranes, making it highly effective against resistant pathogens including Pseudomonas aeruginosa and Acinetobacter baumannii.
Typical dosing ranges from 2.5 to 5 mg/kg daily, divided into multiple doses based on kidney function and infection severity.
While effective, common side effects include nephrotoxicity and neurotoxicity, requiring careful monitoring of kidney function and neurological symptoms during treatment. Less frequent adverse effects may include fever, rash, and gastrointestinal disturbances.
This medication demands professional medical supervision and is typically administered in hospital settings. Ideal for healthcare providers managing complicated infections in critically ill patients where conventional antibiotics prove insufficient.