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Ganaton (Itopride Hydrochloride)

Ganaton (Itopride Hydrochloride)

Regular price ₱2,000.00 PHP
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Unit price ₱66.67 each
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Ganaton (Itopride Hydrochloride) 50 mg is a prescription gastrointestinal prokinetic medication designed to treat chronic gastritis and non-ulcer dyspepsia. This medication works by enhancing acetylcholine action in the digestive tract, promoting normal gastrointestinal motility and relieving symptoms including abdominal bloatedness, upper abdominal discomfort, heartburn, nausea, and vomiting.

Each tablet contains 50 mg of itopride hydrochloride as the active ingredient. The recommended adult dosage is one tablet taken orally three times daily before meals, with treatment typically spanning up to eight weeks. The medication is rapidly absorbed from the gastrointestinal tract, reaching peak plasma levels within 30 to 45 minutes, with a terminal half-life of approximately six hours. Food does not affect its bioavailability, making it convenient for flexible administration schedules.

Ganaton is metabolized primarily through hepatic pathways via flavin-dependent monooxygenase, with metabolites excreted mainly through the urine. Clinical pharmacokinetic studies demonstrate linear pharmacokinetics with minimal accumulation across therapeutic doses ranging from 50 to 200 mg three times daily. The medication exhibits approximately 96% plasma protein binding, predominantly to albumin.

This medication is contraindicated in patients with hypersensitivity to itopride hydrochloride or any formulation excipients, as well as in conditions where increased gastrointestinal motility could be harmful, such as gastrointestinal hemorrhage, mechanical obstruction, or perforation. Anticholinergic drugs may reduce its prokinetic effectiveness. Potential adverse reactions include dizziness, headache, diarrhea, constipation, rash, and elevated liver enzyme levels, though serious events are rare.

Store Ganaton at temperatures not exceeding 30°C. Available in packs of 30 tablets. This is a prescription medication requiring healthcare provider authorization.
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