Renzat (Azathioprine)

Azathioprine is a prescription medicine that belongs to the class of drugs called immunosuppressants.

• Azathioprine is a prodrug (it gets converted in the body to 6-mercaptopurine), which suppresses the immune system by interfering with DNA synthesis in immune cells.

• It reduces the activity of overactive immune responses.

Main Uses

1. Autoimmune diseases – to control conditions where the immune system attacks the body’s own tissues, such as:

• Rheumatoid arthritis
• Systemic lupus erythematosus (SLE)
• Inflammatory bowel disease (Crohn’s disease, ulcerative colitis)
• Autoimmune hepatitis
• Certain dermatologic conditions (e.g., pemphigus)

       2. Organ transplantation – used to prevent rejection of transplanted organs (kidney, liver, heart, etc.) by suppressing the immune response.

Contraindications

• Hypersensitivity to azathioprine
• Pregnancy (for RA treatment)
• Concurrent use with allopurinol or febuxostat without dose adjustment (risk of toxicity)

Dosage: The dosage of this medicine depends on the prescription and instruction given by your doctor.

Precautions: Do not take this medicine without any medical consultation with your doctor.